1. Injury concerns for Antonio Gates yet again

The knee injury Gates’ sustained against the Packers in Week 6 was reportedly not serious. Those reports may have been wrong, or perhaps a recently unroided 35-year-old simply doesn’t heal that quickly. Either way, there’s reason for concern now.

Gates came out of the bye still nursing the knee issue, getting in a limited practice on Wednesday. Things took a turn for the worse Thursday as he sat out with a hip injury, and there’s speculation it’s a result of compensation. Given how bad Gates looked in the game before the bye and these continued issues, I’m unlikely to roster him this week even if he’s active. I’m more on Stevie Johnson with Gates, Ladarius Green (ankle), Malcom Floyd (shoulder) and Keenan Allen (kidney) are either out or hobbled.

2. Darren McFadden added to injury report

Mid-week additions to the injury are never a good sign. So when McFadden popped up “limited” on Thursday with a groin issue, eyebrows were raised. He’s still expected to play Sunday at Miami, but this is a guy who has a long injury history and has touched the ball 26.2 times per day over the last four weeks while playing on 79.7 percent of the snaps. It wouldn’t surprise me at all if he’s a little worn down. So even with Tony Romo back in the lineup and a plus matchup, there are other running backs I feel safer with for now. Perhaps that will change if we get positive news by Sunday morning.

3. 49ers not expected to have Carlos Hyde again

In the first game of the Niners’ new Blaine Gabbert era, they were home against the Falcons. This week is a whole other story as they are at Seattle to face a desperate Seahawks team coming off a loss. They also got some bad news Thursday as Carlos Hyde (foot) missed another practice, leaving him very doubtful. Gabbert will have Shaun Draughn, Kendall Gaskins and Tarvaris Cadet at running back. Meanwhile, Anquan Boldin (hamstring) remained limited in practice and we know Vernon Davis is gone. Paying $4000 for a defense does not sit well with me given the volatility at the position. But there’s no doubt SEA D/ST is far and away the best option this week.

4. Emmanuel Sanders should be available for Brock’s debut

Sanders had to talk his way onto the field last week and ended up playing on just 24-of-73 snaps in the ugly loss to the Chiefs. That’s a problem for the Broncos, as they have little depth behind Manny and Demaryius Thomas. Bennie Fowler and Andre Caldwell are the No. 3 and 4 wideouts. So it’s good news for Brock Osweiler and the team as a whole that Sanders got in a limited practice Thursday and coach John Fox said he expected his No. 2 receiver to be a full go against the Bears Sunday. Sanders is a weak play at (possibly) less than 100 percent for $7000, but the matchup is right and he is getting a quarterback upgrade.