The undefeated 49ers are coming off their most dominant victory of the season, crushing the Panthers 51-13. They improved to 5-2 ATS, but the Cardinals are a sneaky 5-3 ATS themselves. Arizona’s three-game win streak came to an end in New Orleans last week, losing 31-9, and failing to cover 12.5 points.
Last week we went 3-2 on plays, improving the season record to 21-15. Here are some bets to consider on TNF:
All odds provided by DraftKings Sportsbook and all odds subject to change.
ARIZONA CARDINALS VS. SAN FRANCISCO 49ERS (8:20 P.M. ET)
Total Receiving Yards: George Kittle OVER 67.5 (-132)
No defense in the NFL has been as bad defending the TE position as the Cardinals. They’ve allowed a 45-531-7 line on 58 targets this season. This basically equates to an average game for Kittle, who’s gone for 66 receiving yards per game through seven outings. He’s been much better of late, though, going for 70-plus yards in three of his past four, with the outlier being 38 yards in a 9-0 game in Washington, which was played in extreme conditions. This matchup lays out the perfect spot for Kittle to go off for one of his biggest yardage numbers of the season.
Player to Score and Team to Win: Tevin Coleman (-167)
We did well on this market last week, parlaying a Dalvin Cook touchdown with a Vikings win. San Francisco is -435 on the ML here and should win with ease. Coleman scored four times in last week’s win, giving him six touchdowns in four games since returning from an ankle injury. The fantasy speculation around the 49ers’ backfield has been confusing at times, but we know Coleman is the red zone back. The game script sets up perfectly for Coleman to find the end zone again in a comfortable win.
Home Team Points: Cardinals UNDER 16.5 (-120)
The 49ers’ defense has been a nightmare for opponents in October. In four games, San Francisco has allowed just 23 total points, with 13 of those points coming in a blowout over Carolina last week. The other team totals this month have been zero from Washington, seven from the Rams and three from the Browns. It’s tough to see the Cardinals getting to 17 in this one.
Spread: SF -10 (-118)
The Cardinals have allowed their opponents to score at least 21 points in each game this season, with an average points per game against sitting just under 28. If the 49ers do the bare minimum that every other team has done — 21 points — they could hold Arizona to 10 points and cover the spread. But San Francisco is coming off 51 points and easily could get into the 30s here. I don’t see this being a difficult cover, going hand-in-hand with the under on the Arizona team total.
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