Chargers Titans Football

The Week 10 main slate features 10 games, with some heavy hitters absent on bye weeks and playing in primetime games. The Broncos, Texans, Jaguars, Patriots, Eagles and Redskins are on bye. The primetime games feature the Chargers vs. Raiders (TNF), the Vikings vs. Cowboys (SNF) and the Seahawks vs. 49ers (MNF).

It’s crucial to have all the latest lineup and injury news when constructing your lineups. Make sure you’re following @DKLive for every update, and also feel free to hit me up on Twitter with any comments or questions — @JulianEdlow.

All lines and odds are provided by DraftKings Sportsbook.



Lamar Jackson, BAL at CIN ($7,300)

Jackson showed us how dominant he can be in the SNF victory over New England. The Bengals rank 31st in DKFP allowed to QBs and have one of the worst run defenses in football. We got a preview of this matchup in Week 6, when Jackson posted a 19-152-1 line as a runner. He’s a much safer play than a banged-up Patrick Mahomes ($7,000) in Tennessee.

Drew Brees, NO vs. ATL ($6,700)

The wave of QB plays for just under $7,000 is really strong. The Falcons have given up some of the biggest games to QBs we’ve seen this season, and Brees is averaging 27 DKFP in the two full games he’s played. He’s in a smash spot here at home out of the bye.

Jameis Winston ($6,800) and Kyler Murray ($6,500) go head-to-head in what should be a shootout. Both defenses have been allowing huge plays through the air, with Tampa Bay allowing the most DKFP to QBs, and Arizona allowing the third-most. With 51.5 projected points, both QBs have 30-DKFP upside here.


Ryan Tannehill, TEN vs. KC ($5,100)

Tannehill has been a spectacular fantasy option since coming on as the starter. In his three full outings, the former Dolphin is averaging 23.5 DKFP, and the Titans haven’t been shy throwing the ball. The Chiefs rank 25th in DKFP allowed to QBs, and Mahomes’ potential return likely would help Tannehill’s value. If Tennessee has to play from behind against a defense that’s allowed big plays through the air, Tannehill’s value only improves.

Other value options: Jacoby Brissett ($6,000)/Brian Hoyer ($5,900), Daniel Jones ($5,700)

Running Backs


Christian McCaffrey, CAR at GB ($10,500)

If you faded McCaffrey in Week 9 because $10,000 seemed like too much, you were wrong. CMC posted another massive game, with more than 150 yards and three touchdowns (40.6 DKFP). While the $500 boost makes it even more difficult to roster him in Week 10, the matchup is nothing to fear. Do what you can to fit CMC in your lineups.

Saquon Barkley, NYG at NYJ, ($8,800)

Barkley had a rough game on the ground against the Cowboys on MNF but somewhat saved his day with six receptions for 67 yards. The Jets provide a really high floor/ceiling matchup for Barkley in Week 10. The Giants are rare favorites, which should help Barkley get more involved on the ground. He’s a lock for 20-plus touches in one of his best matchups of the season.


David Montgomery, CHI vs. DET, ($5,300)

There’s some appealing RB value this week. Some big names have hit low salary marks, and we also have some plays that’ve been thrusted into larger roles. Montgomery has been a difficult fantasy option to trust, but the Bears seem like they finally have committed to the rookie. Montgomery’s racked up 41 carries and seven receptions for 223 yards and three touchdowns over the past two games, averaging 25 DKFP in those outings. The Lions allow the most DKFP to the RB position in the NFL, so if there was ever a spot to keep the momentum rolling, this would be it.

Other value options: David Johnson ($5,700 – if healthy), Devonta Freeman ($5,100), Devin Singletary ($5,000), Joe Mixon ($4,700), Kalen Ballage ($3,800)

Wide Receivers


Michael Thomas, NO vs. ATL, ($8,300)

We had a lack of WR1 options on last week’s main slate, so Thomas is welcomed back this week, even at a season-high salary. Thomas has been the most consistent WR option in fantasy this season, which is saying a lot with only four touchdowns through eight games. Thomas was targeted at least 11 times in each of his past four games and gets a dream matchup against the Atlanta secondary at home. The Falcons have allowed the fifth-most DKFP to WRs this season.

Mike Evans, TB vs. ARI, ($7,600)

Evan’s stock had never been lower than it was following a goose egg in Week 5. He was having a terrible season, with the majority of his numbers coming in a big Week 3 game against the Giants. Since Week 5, though, Evans has brought in 32-of-45 targets for 474 yards and three touchdowns — an average of more than 35 DKFP. Now he has a home matchup against a terrible Arizona defense, leaving him with the upside for another elite game.


Jamison Crowder, NYJ vs. NYG, ($5,000)

As bad as Sam Darnold ($5,800) has been, Crowder actually has built up a nice game log with Darnold at QB. Crowder’s been targeted at least nine times in three of Darnold’s five starts, scoring 15 or more DKFP in all three of them (more than 22 in two of them). The Giants have allowed the third-most DKFP to WRs, leaving Crowder in a pretty safe spot in Week 10.

Other value options: Zach Pascal ($5,300), DeVante Parker ($4,800), Tyler Boyd ($4,700)

Tight Ends


Austin Hooper, ATL at NO, ($5,500)

No matter the QB in Atlanta, Hooper’s maintained his consistent value. His salary seems to have leveled off here, despite arguably being the best fantasy TE this season. His 52-591-5 line through eight games is good for an average of 18.6 DKFP. Now he goes to New Orleans as a huge underdog, playing in the Superdome. This is a high-upside spot.


Cameron Brate, TB vs. ARI ($3,700)

Brate (ribs) was a bust in Week 9. He clearly wasn’t healthy, which led to zero targets and other TEs playing over him. Assuming he can get healthy for Week 10, Brate has a spectacular matchup. The Cardinals are allowing the most DKFP to the TE position this season.

Other value options: Jack Doyle ($3,600), Ryan Griffin ($3,100)

Defense/Special Teams


Colts D/ST vs. MIA ($3,500)

Miami has gained some momentum (and even a win) over the past few weeks, but things get much tougher in this spot. Indy’s coming off a tough loss in Pittsburgh and needs this win to keep fighting for its division. This D/ST has been very solid over the past month, scoring at least 7.0 DKFP in each of the past four games.


Steelers D/ST vs. LAR ($2,600)

The Steelers’ D/ST just keeps producing, particularly at home. It’s scored at least 11 DKFP in six consecutive games and is averaging 13.8 DKFP in five home games. The Rams clearly aren’t the high-powered offense we knew last season and historically have struggled away from home.

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I am a promoter at DraftKings and am also an avid fan and user (my username is jedlow) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.