Week 5 was loaded with high-scoring plays, most of which were highly owned. Will Fuller, Aaron Jones and Christian McCaffrey all topped 50 DKFP, which made cash lines much higher than usual. In Week 6, the main slate drops down to just 10 games — more teams are on bye, and the London game between the Buccaneers and Panthers has an early start time (yes, that means no CMC on the main slate).

Outside of the London game, we also have Patriots vs. Giants on TNF, Chargers vs. Steelers on SNF and Packers vs. Lions on MNF. The Bills, Bears, Colts and Raiders will be on bye.

It’s crucial to have all the latest lineup and injury news when constructing your lineups. Make sure you’re following @DKLive for every update, and also feel free to hit me up on Twitter with any comments or questions — @Julian Edlow.

All lines and odds are provided by DraftKings Sportsbook.



Patrick Mahomes, KC vs. HOU ($7,500)

After playing to his floor in Week 4 in Detroit, we actually saw another Mahomes floor game on SNF against the Colts. It was his second consecutive game with 21 DKFP, although Mahomes was battling an ankle injury during the contest. The Colts also used a spectacular game plan to keep Mahomes from touching the ball for more than a few minutes in the second half.

Consider Week 6 a second chance at a bounce-back week, but with a spectacular matchup. Matt Ryan ($6,400) just went for 36 DKFP in this matchup last week, trying to keep pace with Houston, which scored 53 points. Assuming Mahomes’ ankle isn’t an issue, he’s still worth paying up for due to the matchup.

Lamar Jackson, BAL vs. CIN ($6,900)

It’s likely going to be a pay-up week at QB. Ryan and Kyler Murray ($6,500) will go head-to-head in Arizona with the total set at 52, and Mahomes will be opposite Deshaun Watson ($6,700), who’s coming off a 45 DKFP game with a 55.5 total set in this matchup.

It would be easy to overlook Jackson, especially coming off his worst game of the season. But he gets a matchup against the Bengals, which has been very favorable for QBs. Cincy’s defense also get gashed by the run, as Murray went for 10-93-1 as a rusher against it in Week 5. That leaves Jackson with a really high floor in this one.


Gardner Minshew, JAX vs. NO ($5,000)

Value is very tough to come across early in the week, particularly on this slate. The Saints’ secondary hasn’t been anything special this season, and the defense is allowing the second-most DKFP to the QB position. Minshew somehow comes down $300 in salary this week, despite having the best fantasy game of his career — 27.16 DKFP in Carolina. A home matchup against New Orleans should be a spot to continue his success. Minshew’s actually been very consistent, averaging 19.5 DKFP.

Other value options: Baker Mayfield ($5,500), Kirk Cousins ($5,200)

Running Backs


Ezekiel Elliott, DAL at NYJ ($8,500)

The game script set up awful for Elliott last week, as the Cowboys got in a big hole early against the Packers. ‘Zeke still saved his fantasy day with a touchdown (17.1 DKFP), but touched the ball just 14 times. It was easy to lose some faith in the Cowboys if you watched their pathetic performance against Green Bay in Week 5, but we also can’t overlook just how good this bounce-back spot is against the Jets. New York’s defense has been pitiful, and the Cowboys will be looking for revenge, coming off consecutive bad losses. As 8.5-point favorites, the game script should be much more favorable this time around.

Dalvin Cook, MIN vs. PHI ($8,400)

There’s no doubt CMC’s been the best fantasy RB this season. However, he was a bust in Week 2 against the Bucs (the same matchup he’ll have this week), which means you could at least make the argument that Cook’s been the most consistent fantasy RB option thus far. Through five games, he’s scored 19 or more DKFP in each game, including 27-plus in four of them. A home matchup against the Eagles should just mean more of the same in Week 6. Until we see Cook have a poor game, he’ll remain a fantastic cash option. He’s a near lock for at least 20 touches per game.


Chase Edmonds, ARI vs. ATL ($4,600)

This is more of a projection play, but David Johnson ($7,600) is no sure thing to play in Week 6 due to the back tightness he played through on Sunday in Cincinnati. We’ll have to monitor DJ’s status this week, but even if he plays, Edmonds saw a season-high 11 touches for 86 yards and a touchdown in the backup role last week. This is a dream matchup against the Falcons, so there’s some upside here either way. If DJ gets ruled out, Edmonds likely becomes the top chalk value on the slate.

Other value options: Chris Thompson ($5,000), Carlos Hyde ($4,400), Kenyan Drake ($4,400)

Wide Receivers


Julio Jones, ATL at ARI ($8,000)

It’s not often we want to target Jones after consecutive duds with his salary on the rise, but this is one of those spots. We just saw Atlanta in a shootout that featured 85 points in Houston, and now they’ll play indoors again, facing an even worse Arizona defense. If there’s a spot for Julio to breakout, this is it. Don’t forget about Larry Fitzgerald ($6,100) for a game stack on the other side, as this Falcons defense just gave up a historic day to Will Fuller ($6,000) — 14-217-3 (56.7 DKFP).

Cooper Kupp, LAR vs. SF ($7,100)

There are a lot of expensive WR options in solid spots in Week 6, but none who’ve been as consistent as Kupp. Kupp’s averaging a slate-high 25.6 DKFP, including three straight games with 29-plus DKFP. Over this three-game span, Kupp’s posted a 29-339-4 line on a ridiculous 44 targets, topping 100 yards with a touchdown in each outing. San Francisco played some cupcakes the first few weeks of the season, and will see a real test on the road against the Rams. Kupp’s floor is as safe as any WR in the NFL right now.


D.J. Chark, JAX vs. NO ($5,500)

Chark essentially profiles as a superstar WR without the brand name at this point — which also means without the salary. He posted an 8-162-2 line for 39.4 DKFP in Carolina last week, boosting his average to 22.3 DKFP through five games. Chark draws a home matchup against a New Orleans defense that ranks 26th in DKFP allowed to WR this season. At this point, he feels at least $1,000 underpriced. Chark could easily be a $7,000 WR on a weekly basis by the time we get to the end of the season.

Other value options: Larry Fitzgerald ($6,100), Calvin Ridley ($5,700), Michael Gallup ($5,600), Preston Williams ($4,100),

Tight Ends


Austin Hooper, ATL at ARI ($5,000)

Hooper’s been one of Ryan’s favorite targets this season, and the TE has arguably benefitted the most from this pass-happy offense. Hooper’s averaging 17.5 DKFP and now faces a Cardinals defense that has allowed the most DKFP per game to the position. This game has tons of fantasy appeal on both sides, but paying up for Hooper at a position of need could arguably provide the most value.


Gerald Everett, LAR vs. SF ($3,600)

Everett’s seen his role grow exponentially the past two weeks. If there was any doubt his 15.4 DKFP output in Week 4 against the Bucs was a fluke, he backed it up with an even better game in Seattle in Week 5. The Rams were forced to pass when they went down 21-0 to the Bucs, but Everett snagged 7-of-11 targets for 136 yards (23.6 DKFP) in a game they tried to feature the run more. It’s worth riding Everett at this price tag, as the Rams may want to keep working him in as the fourth option in the pass game.

Other value options: Will Dissly ($4,900), Jared Cook ($3,400), Ricky Seals-Jones ($3,300)

Defense/Special Teams


Redskins D/ST at MIA ($3,200)

All the defenses at the top of the board this week are overrated in my mind. Call me crazy, but it’s not a bad spot for Washington. It’ll be playing under a new head coach and will face a Miami offense that’s been inept through its first four games. Washington’s scored 5.0 or more DKFP in three straight, including against the Patriots. It had four sacks and an interception, which means there is potential for much more against the Dolphins.


Jets D/ST vs. DAL ($1,500)

I don’t love this spot, but I’m also not afraid to target the Jets in a tournament for three reasons. The Cowboys found most of their production against terrible teams to begin the season, and have struggled against two solid teams since. The Jets’ defense has still managed to put up 10.8 DKFP per game, which isn’t bad for the cheapest option on the board. Speaking of which, this new salary floor for D/ST means even more savings. At just $1,500, rostering the Jets opens up the room to jam even more studs into your lineup.

I am a promoter at DraftKings and am also an avid fan and user (my username is jedlow) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.