Houston Astros v Seattle Mariners

Wednesday’s main fantasy baseball slate on DraftKings has 12 MLB games. Tuesday saw two notable fantasy studs leave their respective games with injuries. Boston Red Sox star OF Mookie Betts re-aggravated his foot injury, and Atlanta Braves star OF Ronald Acuna Jr. left his game with hip tightness. In addition, Houston Astros star SS Carlos Correa was a late scratch from Tuesday’s lineup due to back tightness, and his status Wednesday is unclear.

While Tuesday’s slate lost some fantasy studs due to injury, Jose Ramirez (hand) made his return to the Cleveland Indians’ lineup and socked two dingers in a seven-RBI effort. Edwin Encarnacion (oblique) is also a candidate to return to the New York Yankees’ lineup Wednesday. On the pitching side, Frankie Montas (suspension) will return and start for the Oakland Athletics against the Los Angeles Angels.

Fantasy owners can receive up-to-the-minute news, analysis and lineups by downloading the DK Live app. You also can follow DK Live on Twitter @DKLive.

Here are a few different hitting stacks fantasy owners can consider using on DraftKings on Wednesday:

1. Houston Astros

The Astros, who have been baseball’s best offense, have a strong matchup against Seattle Mariners left-handed pitcher Yusei Kikuchi ($5,200). Kikuchi has been home run prone, allowing more than two home runs per nine innings, which has contributed to allowing a heavy .247 isolated power to opponents, well above the league average of .183. Kikuchi does not miss many bats, striking out just 16% of batters, below the SP league average of 22%. Kikuchi’s combination of poor strikeouts and elevated home runs has contributed to a poor 5.85 FIP. The left-handed Kikuchi also is facing a Houston lineup that is primarily right-handed, giving the Astros the platoon advantage. The Astros are in a good spot for extra-base hits and contact against a pitcher who has been prone to giving up extra base-hits and does not strike many batters out.

Players to consider

George Springer ($5,700)
Yordan Alvarez ($5,500)
Alex Bregman ($5,200)
Jose Altuve ($4,900)
Carlos Correa ($4,800; DTD)
Yuli Gurriel ($4,700)
Michael Brantley ($4,300)


2. Cleveland Indians

The Indians have a highly appealing matchup against Chicago White Sox left-handed pitcher Ross Detwiler ($5,900). Detwiler has been one of the most home run prone pitchers in baseball, allowing the fifth highest home run rate among pitchers to have thrown at least 50 IP in 2019. Detwiler has allowed extremely poor contact quality, allowing batters to produce an expected wOBA of .397 based on the exit velocities and angles of their batted balls, significantly worse than the league average of .319. Detwiler does not strike many batters out, striking out just 15% of batters faced, well below average. Detwiler’s home run proneness and lack of strikeouts has contributed to him posting an ugly 7.28 FIP, third worst among all pitchers to have thrown at least 50 IP. The Indians are in a good spot for power and contact in this matchup, and they are getting a park upgrade on the road in hitter-friendly Chicago.

Players to consider

Francisco Lindor ($5,300)
Oscar Mercado ($5,200)
Carlos Santana ($5,000)
Jose Ramirez ($5,000)
Yasiel Puig ($4,500)
Franmil Reyes ($4,100)


3. Toronto Blue Jays

The Blue Jays have a home matchup in hitter-friendly Toronto against a Baltimore Orioles pitching staff that has allowed the most home runs in major league history. RHP Gabriel Ynoa ($4,000) is starting the game for Baltimore, and Ynoa has been home run prone, which has contributed to him allowing an elevated .251 isolated power to opponents. Ynoa strikes out very little batters, striking out 13% of batters faced, significantly below average. The lack of strikeouts and home run proneness has him posting a 6.11 FIP, third worst among all pitchers to have thrown at least 100 IP in 2019. Ynoa is backed by an Orioles bullpen that is the worst in baseball by FIP and second worst by ERA.

Players to consider

Cavan Biggio ($5,000)
Randall Grichuk ($4,400)
Vladimir Guerrero Jr. ($4,000)
Rowdy Tellez ($3,700)
Billy McKinney ($3,600)


4. Washington Nationals

Philadelphia Phillies LHP Drew Smyly ($6,600) has the worst FIP among all pitchers to have thrown at least 100 IP. Smyly’s poor 6.51 FIP is on the back of a very elevated home run rate, allowing 2.59 home runs per nine innings, also the worst mark among pitchers to have thrown 100 IP. Smyly’s extra base hit proneness has him allowing an isolated power of .288 to opponents, an extremely elevated number. Nationals batters are in a good environment for power hitting in the matchup.

Players to consider

Trea Turner ($5,400)
Anthony Rendon ($5,400)
Howie Kendrick ($5,300)
Juan Soto ($5,100)
Victor Robles ($4,100)
Ryan Zimmerman ($3,800)


5. Boston Red Sox

The Red Sox are on the road in hitter-friendly Arlington, one of the best hitter’s parks in baseball, and face fairly mediocre pitching opposition in Koby Allard ($7,400). Allard also does not miss many bats, striking out less batters than average, which could help Boston put the ball in play in a great hitter’s park.

Players to consider

Mookie Betts ($5,600; DTD)
Rafael Devers ($5,300)
Xander Bogaerts ($5,200)
J.D. Martinez ($5,000)
Christian Vazquez ($4,900)
Andrew Benintendi ($4,200)


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I am a promoter at DraftKings and am also an avid fan and user (my username is timfinn521) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.